The Category 4 storm is expected to make landfall near West Palm Beach and Melbourne overnight and then track north along the Atlantic coast racking up as much as $50 billion in economic losses.
A strengthening Hurricane Matthew is on course to batter the Florida, Georgia and South Carolina coasts, where it could cause $15 billion in U.S. losses.
Hermine is weakening as it moves farther inland across Floridas Panhandle and southeastern Georgia, after largely sparing energy assets in the Gulf of Mexico.
The new tool will let forecasters target potentially life and property threatening downpours street by street, giving people more time to get out of harms way.
The Atlantic basin will see the most named storms since the 2012 season, with five to eight of those strengthening into hurricanes by Nov. 30, NOAA predicts.
Tropical Storm Earl, forecast to grow into a hurricane, may just graze Mexicos oil-rich Bay of Campeche as it heads west toward the Honduras Bay Islands before making landfall in Belize within the next 24 hours.