(Bloomberg) – Hurricane Irma hopscotched up Florida's west coast Sunday, making two landfalls and driving a wall of water and winds that submerged Miami and had the Tampa Bay area readying for a deluge of a sort unseen in decades.

220-mile reach

Irma's 220-mile reach is so long that cities on the state's southern and eastern extremes were hit with surges and winds high enough to topple cranes in Miami, where the flooded Brickell financial district looked like a swift river. Early reports suggested that the low-lying Florida Keys were devastated, with photos showing cars submerged almost to their roofs. The U.S. military began a relief mission, sending tarpaulins, food, water and medical supplies.

Just over two weeks after Hurricane Harvey struck the heart of U.S. energy production in Texas, Irma is threatening another region. By 5 p.m. Sunday, it was a Category 2 storm with top winds of 110 miles per hour, the U.S. National Hurricane Center said. While initial estimates saw a $200 billion loss, as the storm weakens on its northerly trek that number could fall.

Its path forced the largest evacuation in Miami-Dade County history and sent millions of Floridians fleeing the state's first major hurricane since Wilma in 2005. It has already laid waste to the small island of Barbuda, killed at least 25 people and left thousands homeless across the Caribbean.

1st landfall over lower Keys as Cat 4

In the U.S., the storm made landfall over the lower Keys about 9 a.m. with Category 4 winds hitting 130 miles per hour (209 kilometers) before starting to weaken. It made a second landfall at Marco Island in the afternoon, then passed 5 miles north of Naples as it headed up the state's west coast toward Alabama and Georgia.